Innovation Acta News
1st TOLERATE Annual Meeting – 20-22 November 2023, Amsterdam
The 1st Annual Meeting for the TOLERATE project has been held in Amsterdam from the 20th to 22nd of November. The event has been organised by the project partner Sanquin with the support of Innovation Acta. The 3-days meeting included the progress meeting with presentations from all the fellows, and three different training courses on scientific and transferable skills.
geneTIGA Annual Meeting in Enchanting Rome on 14th -15th November
On 14 and 15 November 2023 INN-ACTA organized the First Annual meeting of geneTIGA project in Italy.
geneTIGA is a Research and Innovation Action funded under Horizon Europe that aims to develop a safe and efficient cell therapy based on genome-edited T cells with redirected specificity to sustainably combat IgA nephropathy (IgAN). geneTIGA specific cell therapy approach is also suitable for other diseases with selective B-cell pathogenesis, such as IgA myeloma and rheumatoid arthritis, but as a blueprint also for diseases of other Ig classes.
We had the pleasure of gathering all consortium members from Germany, Spain, Norway, Denmark, UK and Switzerland, in the breathtaking city of Rome for a very productive and inspiring meeting. The meeting provided a valuable opportunity for us to discuss about the work accomplished and progresses achieved in the past year and about the new challenges ahead. The exchange of ideas was lively, with each member contributing their unique perspectives and expertise to the conversation.
Rome, with its rich history and cultural significance, provided the perfect backdrop for fostering a sense of unity among consortium members.
We look forward to leveraging the insights gained during this meeting to propel our project forward.
GUIDE.MRD First face-to-face meeting on 22nd and 23rd of October in Madrid
The GUIDE.MRD consortium partners met for the first face-to-face annual meeting hosted by Dr. Núria Malats at CNIO - Spanish National Cancer Research Centre, in Madrid, Spain, from 22-23 October 2023 and organized with the support of Innovation Acta S.r.l.
During the first day first day the monthly Steering Committee meeting took place in presence, chaired by the Academic Coordinator, Prof. Klaus Pantel, Universitätsklinikum Hamburg Eppendorf and the Project Leader, Bristol Myers Squibb, followed by a networking evening hosted by CNIO with fruitful discussions on the GUIDE.MRD project and most recent data from ESMO 2023.
The second day was opened by welcoming remarks from the Academic Coordinator and a presentation on the hosting partner CNIO. Thereafter, the Work Package leaders Ellen Heitzer (Medical University Graz, Austria, WP2) and Claus Lindbjerg Andersen (Aarhus University Hospital, Denmark, WP3) as well as clinical study leaders Matthias Löhr (Karolinska Institute, Sweden, WP3) and Jeroen Hiltermann (University Medical Center Groningen, The Netherlands, WP3) presented the most recent data and progress of the project.
Over 40 participants from the 22 partners engaged in very productive discussions on the results reached by the consortium in the first 6 months as well as some of the main challenges and opportunities. It was also noted how input from patients has been incorporated since this early phase of the project through our partners The Synergist, Lung Cancer Europe, Digestive Cancers Europe and the project's Patients Advisory Board, especially in relation to the first three clinical trials.
The B-specific Kick-Off meeting, 23rd October 2023 in Leiden
The B-specific consortium led by Amanda Foks (Leiden Academic Centre for Drug Research, Leiden University, The Netherlands) successfully kicked-off the project B-specific (B-cell related gene and protein markers with prognostic and therapeutic value for CVD). The event was held on the 23rd of October 2023 at the Faculty Club (Academy Building) in Leiden (The Netherlands). Thanks to European Innovation Council (EIC) (Grant Nr. 101115159) for supporting the research to discover new biomarkers and therapeutic targets for atherosclerosis.
B-specific project starts on the 1st of October 2023
We are glad to announce that the B-specific project, funded by the European Innovation Council under the 2022 Pathfinder Challenge call will officially start on the 1st of October 2023. During the next four years, the international consortium coordinated by Leiden University (The Netherlands) will focus on the discovery of novel biomarkers of cardiovascular disease to accelerate the impact of these in clinical practice. Innovation Acta, as part of the Consortium, will assist the administrative bodies of the Partners’ institutions and will provide support to communication activities. The Kick-off meeting will be held on the 23rd of October 2023 in Leiden (The Netherlands).
T-FITNESS meeting in Capri
On the 18th and 19th of September, the T-FITNESS consortium met in the beautiful island of Capri for the first annual meeting. This EIC Pathfinder grant aims to explore bold ideas for radically new technologies. In particular, T-FITNESS aims to revolutionize current T cell immunotherapies by developing an innovative platform to overcome T cell exhaustion. During the meeting, the partners discussed the remarkable progress made within just one year of the project's inception and exchanged valuable insights regarding the challenges ahead.
It’s official: UK to associate to Horizon Europe
After multiple false dawns, London and Brussels have finally agreed a deal to allow the UK to rejoin. The UK will also join the Copernicus space programme but is out of Euratom and the ITER fusion project. UK will be able to fully participate from 1 January 2024 in the 2024 work programme – a list of the projects Horizon Europe will fund that year - and onward, including 2024 calls that open this year. For calls under the 2023 work programme, however, UK researchers will still have to use UK backup guarantee scheme to fund their participation in any Horizon projects. The agreement is only until the end of Horizon Europe in 2027.
Full text and additional articles here:
It’s official: UK to associate to Horizon Europe | Science|Business (sciencebusiness.net)
How the UK and EU did a deal over Horizon Europe | Science|Business (sciencebusiness.net)
Science world welcomes UK back to Horizon as government celebrates ‘bespoke deal’ | Science|Business (sciencebusiness.net)
01 September 2023 exTra Project officially started!
exTra is a Doctoral Network funded under Horizon Europe Programme. exTra Consortium is a research network of leading European scientists from academia and industry, experts in clinical transplantation, immunology, pharmaceutical development and medical device manufacture to address key questions on extracorporeal photopheresis (ECP) through a coordinated, interdisciplinary effort. exTra proposes 11 independent doctoral research projects with the ambition of providing its trainees with a comprehensive understanding of basic and translational immunology, especially relating to development and licensing of new immunotherapies. Through its research and training activities, the exTra project will contribute to scientific advancement and innovation in Europe, ultimately leading to societal and economic benefits stemming from clinical innovations in transplant immunotherapy and beyond. Innovation-Acta is Associated Partner of the Network for management, training and communication activities.
INsTRuCT final meeting on 31st May and 1st June 2023 in Regensburg
INsTRuCT Network members from 13 beneficiaries, the 15ESRs, the associated industrial partners Sanofi, AstaZeneca, UCB Biopharma and InnovationActa, met in Regensburg for the final meeting. The meeting included outstanding presentations from all 15ESRs, now at the third year of their research work, who reported about their individual projects and achievements in the in the myeloid regulatory cell (MRC)-based therapy research. A Networking session for ESR and commercial partners was part of the programme. INsTRuCT is funded under Horizon 2020 research and innovation programme under the Marie Skłodowska-Curie grant agreement No 860003. The project combines excellence in basic, preclinical and translation research with an outstanding programme of scientific education and practical training for early stage researchers, who are driving critical advancement in the field.
IMMUTOL Kick off meeting on 24th and 25th of May 2023 in Milan
The IMMUTOL Consortium, led by Silvia Gregori (San Raffaele Telethon Institute for Gene Therapy– SR-Tiget) successfully kicked-off the project "Advanced Antigen-Specific Dendritic Cell-Based Therapy to Re-establish Tolerance in Immune-Mediated Diseases". The hybrid event was held on 24th and 25th of May at Fondazione Telethon, Milano (Italy). Innovation Acta organized and joined the meeting. Thanks to EU Horizon Europe (Grant Agreement Nr.: 101080562) for supporting fast-tracking the development and validation of an Advanced Therapy Medicinal Product based on engineered dendritic cells to treat patients with immune-mediated diseases with an unmet medical need, in particular multiple sclerosis.
GUIDE.MRD project starts on 1st May 2023
On May 1st 2023 just started GUIDE.MRD, a five-year Innovative Health Initiative project. GUIDE.MRD is a consortium of leading academics, technology companies, pharmaceutical companies, patient organizations, and experts in multi-stakeholder engagements. Innovation Acta, as part of the Consortium, will provide support to the administrative management of the project, and to communication activities. GUIDE.MRD will tackle the critical questions by developing reference standards for circulating tumor DNA (ctDNA) diagnostics, clinically validate promising ctDNA diagnostics and develop data to guide the use of multi-modal therapies with a noninvasive diagnostic test. With robust engagement with regulatory authorities, payers and importantly patients themselves, we will develop recommendations and guidelines based on objective data to use ctDNA diagnostics to guide multimodal therapy selection to improve patient outcomes. GUIDE.MRD Kick off meeting will be held online on 29th – 30th June 2023
IMMUTOL project starts on 1st May 2023
We are thrilled to announce that 1st of May 2023 is the official start of IMMUTOL. For the next four years, in the frame of this Research and Innovation Action, the main goal will be to fast-track the development and validation of an advanced therapeutic medicinal product, aimed to treat patients with immune-mediated diseases. IMMUTOL will develop a more potent and durable treatment for autoimmune diseases with an unmet medical need, in particular Multiple Sclerosis.
The consortium gathers experts and institutions from different sectors, from research institutions and academia, patients’ association to hospitals and corporate SME. Innovation Acta, as part of the Consortium, will provide support to the administrative management of the project, and to communication activities.
The Kick-off meeting will be held on 24th and 25th of May 2023 in Milano (Italy).
Doctoral Networks Call 2022 - Innovation Acta participation
Doctoral Networks Call 2022 - Evaluation Results
The European Commission has completed the evaluation of the 2022 MSCA Doctoral Networks (DNs) call and published the evaluation results on 16 March 2023.
Of the 946 submitted proposals, 149 were invited for grant preparation, resulting in an overall success rate of 15.8% for the 2022 call. The success rate in the 2022 call is 2.4 percentage points higher than in 2021 (13.4%).
It is expected that the first grant agreements will be signed by July 15th 2023.
Information on the selected projects will be published on CORDIS after that date.
The projects’ starting date will be between 01/09/2023 to 01/03/2024
PROTO Kick-off meeting 28th February-1st March 2023 in Berlin
We successfully kicked-off our PROTO consortium during these exciting two last days! Thanks to EU Horizon Europe (Grant Nr. 101095635) for supporting our endeavour to prevent, early diagnose and treat osteoarthritis.
Extension to support UK Horizon Europe applicants
UK Government ensures that eligible, successful UK applicants will continue to be guaranteed funding. The guarantee will be in place to cover all Horizon Europe calls that close on or before 31st of March 2023. Eligible, successful applicants to Horizon Europe will receive from the UK Research and Innovation (UKRI) the full value of their funding at their UK host institution for the lifetime of their grant. View more
To be eligible the applicant must: (i) be based in the UK; (ii) have been successful at applying for a Horizon Europe grant with final submission deadlines on or before 31st of March 2023 and (iii) have been included on the initial grant proposal as a ‘beneficiary‘ with an assigned budget. In parallel, the UK government continues to push for Association to EU programs.
PROTO project officially started!
January 1st marks the official start of PROTO, a five -year international project coordinated by Charité - Universitätsmedizin Berlin, Germany. The Kick-off meeting will be held in Berlin on 28 February-1st March 2023. PROTO will develop novel interventional strategies aimed at tackling the development and progression of osteoarthritis. The PROTO consortium gathers experts and institutions from different sectors, from academia to SMEs and patient organizations. They all focus on distinct and complementary steps in the clinical research on musculoskeletal diseases, from ATMP manufacturing and characterization, their application in the clinic, implementing biomarker analysis, metabolomics and genetic profiling and patient input and information. Innovation Acta is part of this great team and ambitious project’s goal.
Innovation Acta wishes you a relaxed Christmas time, Nice Holiday Season and a Happy, Healthy and Successful 2023!
New Health Cluster Work Programme
The new Work Programme 2023-2024 of the Health Cluster has been published. In our website you can find a selection of calls, while the whole Health Work Programme is available at the link below
New IHI Work Programme
The 3rd IHI call is now open with a deadline on March 15th, 2023. Topics are:
- Topic 1: Screening platform and biomarkers for prediction and prevention of diseases of unmet public health need
- Topic 2: Patient-generated evidence to improve outcomes, support decision making, and accelerate innovation
- Topic 3: Combining hospital interventional approaches to improve patient outcomes and increase hospital efficiency
- Topic 4: Strengthening the European translational research ecosystem for advanced therapy medicinal products (ATMPs) for rare diseases
- Topic 5: Digital health technologies for the prevention and personalised management of mental disorders and their long-term health consequences
New EIC Work Programme
The new EIC Work Programme 2023 has been published. Main calls in 2023 are summarised below
New Mission Work Programme
The new Mission Work Programme 2023-2024 has been published. In our website you can find a selection of calls, while the whole Mission workprogramme is available at the link below
New MSCA Work Programme
The new MSCA Work Programmehas been published.
TOLERATE starts today!
October 1st marks the official start of TOLERATE, a Marie Skłodowska-Curie Doctoral Network (MSCA-DN) funded by the European Union Horizon Europe Programme. TOLERATE aims at training 8 Doctoral Candidates to acquire the skills to develop different innovative strategies to treat autoimmune diseases, to identify the most promising strategies or a combination of strategies, to setup clinical trials and to develop a roadmap to bring a novel therapeutic agent to the market. As Associated Partner, Innovation Acta will provide support to the administrative management of the project, and to communication activities.
T-FITNESS project official start
September 1st marks the official start of T-FITNESS, a four-year international project coordinated by the Leibniz Institute for Immunotherapy (LIT), Regensburg, Germany. T-FITNESS is one of 39 projects -out of 403 proposals- selected for funding by the European Innovation Council in the 2021 Pathfinder Challenge call. Innovation Acta will provide support to this great team and ambitious project’s goal aiming to revolutionize current T cell immunotherapies.
The European Commission has recently launched a pilot evaluation process within the EIC Pathfinder programme under the so-called "Rebuttal Phase"
Here some useful information on how to prepare the rebuttal letter.
StairwAI 1st Open Call
Artificial intelligence: the first call of the StairwAI project is now open.
StairwAI, is a European Union-funded project which aims to facilitate the engagement of low-tech companies in the AI4EU platform (a one-stop-shop for anyone looking for Artificial Intelligence (AI) knowledge, technology, tools, services, and experts) and the implementation of AI.
The project has now launched its first open call or funding opportunity for low-tech small and medium-sized companies (SMEs) that do not have immediate access or knowledge on AI techniques to improve their products, services, or value chains with the support of AI Experts and High Computing Cloud Providers.
NextGenerationEU: European Commission raises 5 billion in additional funds for recovery
With the first bond issue by syndication in 2022, the European Commission raised today an additional €5 billion in NextGenerationEU funds on behalf of the EU. Maturing on 6 July 2051, the 30-year bond, executed as an increase in an existing EU bond, brings the total funding raised under the programme to €78.5 billion. The successful placement of the Commission will help to boost Europe’s recovery from the COVID-19 pandemic.
Ideas Powered for Business
Intellectual property: launch of the "Ideas Powered for Business" website, the new information hub for European SMEs
The European Intellectual Property Office (EUIPO) has created a centralised information hub for businesses interested in intellectual property aspects. With the new “Ideas Powered for Business” website, the EUIPO is intensifying efforts to help entrepreneurs, start-ups, and small to medium-sized enterprises (SMEs) to alleviate some of the challenges they face in relation to intellectual property (IP).
The platform offers information geared towards supporting SMEs and other stakeholders to develop their business strategy and accelerate business growth with a clear focus on IP and IP rights, such as a training area, a database of IP services, an events section, and other resources.
EIC Work Programme 2022
The Commission adopted today the 2022 work programme of the European Innovation Council. It opens funding opportunities worth over €1.7 billion in 2022 for breakthrough innovators to scale up and create new markets, for example in quantum computing, new generation batteries and gene therapy. Launched in March 2021 as a major novelty of the Horizon Europe programme, the European Innovation Council has a total budget of over €10 billion between 2021 and 2027.
Linee Guida per le iniziative PNRR
Sono state pubblicate le Linee Guida del Ministero della Salute e MUR per i prossimi bandi del Piano complementare al Piano Nazionale di Ripresa e Resilienza per le Iniziative di ricerca per tecnologie e percorsi innovativi in ambito sanitario e assistenziale e per l’Ecosistema innovativo della salute.
Commission selects first EIC Transition projects to take breakthrough technologies from the lab into the real world
The European Innovation Council (EIC) has selected 42 projects following a first ever EIC Transition calls for proposals. Successful proposals, selected among 292 submitted, will receive altogether €99 million of EU funding.
ERC-funded Research wins most of new eu innovation grants
25 out of 42 recipients of the European Innovation Council’s new “Transition” funding originated from research funded by the ERC. The new grants will help take breakthrough technologies from the lab into the real world.
Open Mission Calls
EU Missions new work program of Horizon Europe: 122.38 million euros are allocated to the first calls of the Mission "Adaptation to Climate Change", which opened on 11 January 2022. The Mission aims to support regions and communities in their adaptation to climate change, including the development of risk assessments, pathways and demonstrators of large-scale innovative systemic solutions that are cost-effective.
EU Missions new work program of Horizon Europe: 119.37 million euros are allocated to the first calls of the Mission "Climate-Neutral and Smart Cities", which opened on 11 January 2022. Other topics will open on April 28, 2022. The Mission intends to invest in new urban planning and design for sustainable, resilient and climate neutral cities, to unlock the innovation potential of public transport as the backbone of urban mobility and to create districts of positive clean energy.
EU Missions new work program of Horizon Europe: 62 million euros are allocated to the first calls for the Mission "Soil health and food", opened on 22 December 2021. Funded projects will support the creation of living labs on soil health and the validation and definition of soil health indicators, as well as the creation of a new generation of soil consultants to guide landowners and land managers in implementing sustainable practices, as well as to guide authorities in decision making for a positive impact on soil health.
EU Missions Cancer
EU Missions new work program of Horizon Europe: 125.65 million euros are allocated to the first calls of the "Cancer" Mission, open from 22 December 2021. The Mission intends to develop new methods and technologies in cancer screening and early diagnosis, establish measures for the quality of life, as well as understand the impact of risk factors and health determinants on cancer development and progression.
Horizon Europe: Tackling diseases 2022
New call: Tackling diseases (Single Stage - 2022). This call aims at supporting activities that are enabling or contributing to one or several expected impacts of destination 3 “Tackling diseases and reducing disease burden”.
Partnerships in Health 2022
New call: European partnership fostering a European Research Area (ERA) for health research. The call is part of Destination 2 - Living and working in a health-promoting environment which aims to promote sustainable and health-friendly living and working environments thanks to a better understanding of environmental, occupational, social and economic risk factors.
JPIAMR 14th Call
JPIAMR is launching an international call for projects under the umbrella of the JPIAMR and within the framework of the ERA-NET JPIAMR-ACTION. The call Disrupting drug resistance using innovative design involves 27 funding organisations from 18 countries. The total estimated call budget is close to 19 million Euro.
Open calls “LIFE”
New call: LIFE-2021-Preparatory Projects as part of the Programme for the Environment and Climate Action (LIFE) Call for proposals. The call is launched in accordance with the 2021-2024 Multiannual Work Programme2 and will be managed by the European Climate, Infrastructure and Environment Executive Agency (CINEA) (‘Agency’).
PNRR Italian calls
Nuovo bando per gli ecosistemi dell’innovazione territoriali
La misura prevede un investimento complessivo di 1,3 miliardi di euro.
Nuovi bandi bandi per le infrastrutture di ricerca e per le infrastrutture tecnologiche di innovazione
La misura prevede un investimento complessivo di 1,58 miliardi di euro.