Get Ready for the Upcoming Horizon Europe Health Calls!

The next Horizon Europe calls under Cluster 1 “Health” are expected to be opened in the coming weeks — and it's time to prepare! These calls will support ambitious, collaborative projects that tackle Europe's most pressing health challenges. With a wide range of topics across key Destinations, there's a wealth of opportunities for researchers, innovators, and stakeholders across the health ecosystem. Whether your work addresses prevention, diagnosis, treatment, or healthcare delivery, there’s a Horizon Europe opportunity for you.


Explore the Full List of Cluster 1 – Health Topics:

  Staying healthy in a rapidly changing society;
  Living and working in a health-promoting environment;
  Tackling diseases and reducing disease burden;
  Developing and using new tools, technologies and digital solutions for a healthy society;
  Maintaining an innovative, sustainable, and competitive EU health industry;
  Ensuring equal access to innovative, sustainable, and high-quality healthcare.

These topics reflect Europe's commitment to a more resilient, equitable, and digitally empowered healthcare system.

Topics Type Budget
(EUR million)
Budget/
project
Number of
projects
expected to be funded
Deadline
Destination - Tackling diseases and reducing disease burden
HORIZON-HLTH-2025-01-DISEASE-01: Testing safety and efficacy of phage therapy for the treatment of antibiotic-resistant bacterial infections RIA 45.00 15.00 3 16 Sep 2025
HORIZON-HLTH-2025-01-DISEASE-03: Development of antibodies and antibody-derived proteins for the prevention and treatment of infectious diseases with epidemic potential RIA 50.00 10.00 5 16 Sep 2025
HORIZON-HLTH-2025-01-DISEASE-04: Leveraging artificial intelligence for pandemic preparedness and response RIA 35.00 6.00 to 8.00 5 16 Sep 2025
HORIZON-HLTH-2025-01-DISEASE-05: Support for the functioning of the Global Research Collaboration for Infectious Disease Preparedness (GloPID-R) CSA 2.00 2.00 1 16 Sep 2025
HORIZON-HLTH-2025-01-DISEASE-06: Implementation research addressing strategies to strengthen health systems for equitable high quality care and health outcomes in the context of non-communicable diseases (GACD) RIA 20.00 3.00 to 4.00 5 16 Sep 2025
HORIZON-HLTH-2025-01-DISEASE-07: Tackling high-burden for patients and under researched medical conditions RIA 30.00 6.00 5 16 Sep 2025
HORIZON-HLTH-2025-03-DISEASE-02-two-stage: Advancing innovative interventions for mental, behavioural and neurodevelopmental disorders RIA 50.00 6.00 to 8.00 7 16 Sep 2025 (stage 1)
Destination - Ensuring equal access to innovative, sustainable, and high-quality healthcare
HORIZON-HLTH-2025-01-CARE-01: End user-driven application of Generative Artificial Intelligence models in healthcare (GenAI4EU) RIA 40.00 15.00 to 20.00 2 16 Sep 2025
Developing and using new tools, technologies and digital solutions for a healthy society
HORIZON-HLTH-2025-01-TOOL-01: Enhancing cell therapies with genomic techniques RIA 50.00 8.00 to 10.00 5 16 Sep 2025
HORIZON-HLTH-2025-01-TOOL-02: Advancing cell secretome-based therapies RIA 40.00 9.00 to 13.00 3 16 Sep 2025
HORIZON-HLTH-2025-01-TOOL-03: Leveraging multimodal data to advance Generative Artificial Intelligence applicability in biomedical research (GenAI4EU) RIA 50.00 15.00 to 17.00 3 16 Sep 2025
HORIZON-HLTH-2025-01-TOOL-05: Boosting the translation of biotech research into innovative health therapies RIA 80.00 4.00 to 8.00 10 16 Sep 2025
Destination - Maintaining an innovative, sustainable, and competitive EU health industry
HORIZON-HLTH-2025-01-IND-01: Optimising the manufacturing of Advanced Therapy Medicinal Products (ATMPs) IA 40.00 6.00 to 8.00 5 16 Sep 2025
HORIZON-HLTH-2025-01-IND-02: Digitalisation of conformity assessment procedures of medical devices and in vitro diagnostic medical devices CSA 4.00 4.00 1 16 Sep 2025
HORIZON-HLTH-2025-03-IND-03-two-stage: Facilitating the conduct of multinational clinical studies of orphan devices and/or of highly innovative (“breakthrough”) devices RIA 40.00 6.00 to 8.00 5 16 Sep 2025 (stage 1)
Destination - Staying healthy in a rapidly changing society
HORIZON-HLTH-2025-03-STAYHLTH-01-two-stage: Improving the quality of life of persons with intellectual disabilities and their families RIA 40.00 6.00 to 8.00 5 16 Sep 2025 (stage 1)
Destination - Living and working in a health-promoting environment
HORIZON-HLTH-2025-03-ENVHLTH-01-two-stage: The impact of pollution on the development and progression of brain diseases and disorders RIA 40.00 6.00 to 7.00 6 16 Sep 2025 (stage 1)
HORIZON-HLTH-2025-03-ENVHLTH-02-two-stage: Advancing knowledge on the impacts of micro- and nanoplastics on human health RIA 40.00 7.00 to 8.00 5 16 Sep 2025 (stage 1)

Spotlight on Cluster 6 – Food, Bioeconomy, Natural Resources, Agriculture and Environment

We’re also highlighting a selection of transformative topics from Cluster 6, focused on:

🌱 Investments in transformative innovations;
♻️ Achieving a circular economy and zero pollution;
🌿 Restoring European biodiversity.

Short selection of transformative topics from Cluster 6

Topic Type Budget
(EUR million)
Budget/
project
Number of
projects
expected to be funded
Deadline
Destination - Fair, healthy and environment-friendly food systems from primary production to consumption
HORIZON CL6-2025-02-FARM2FORK-02: Additional activities for the European partnership on animal health and welfare COFUND 120.00 120.00 1 16 Sept 2025
HORIZON-CL6-2025-02-FARM2FORK-03-two-stage: Making food systems more resilient to food safety risks through the deployment of technological solutions IA 12.00 6.00 2 04 Sept 2025 (stage 1)
Destination - Clean environment and zero pollution
HORIZON-CL6-2025-01-ZEROPOLLUTION-04: Towards a comprehensive European strategy to assess and monitor aquatic litter including plastic and microplastic pollution RIA 6.00 6.00 1 17 Sept 2025
HORIZON-CL6-2025-01-ZEROPOLLUTION-05: EU-India cooperation on cumulative impacts of marine pollution on marine organisms and ecosystems RIA 12.00 6.00 2 17 Sept 2025
HORIZON-CL6-2025-01-ZEROPOLLUTION-07: Reducing pollution from the food and drink industries IA 12.00 6.00 2 17 Sept 2025
Destination - Land, ocean and water for climate action
HORIZON-CL6-2025-02-CLIMATE-03: Understanding and managing medium and longer-term challenges and opportunities for agriculture stemming from shifting climatic zones and changing agroecological environments RIA 10.00 5.00 2 16 Sept 2025
HORIZON-CL6-2025-02-FARM2FORK-04: Enhancing plant protein production to bolster the resilience of agricultural systems and EU self-sufficiency in plant protein used as feed RIA 11.00 5.50 2 16 Sept 2025
HORIZON-CL6-2025-02-FARM2FORK-07: Fostering animal breeding and genetics for climate change adaptation and mitigation, improved robustness and resilience RIA 12.00 6.00 2 16 Sept 2025

   


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