The next Horizon Europe calls under Cluster 1 “Health” are expected to be opened in the coming weeks — and it's time to prepare! These calls will support ambitious, collaborative projects that tackle Europe's most pressing health challenges. With a wide range of topics across key Destinations, there's a wealth of opportunities for researchers, innovators, and stakeholders across the health ecosystem. Whether your work addresses prevention, diagnosis, treatment, or healthcare delivery, there’s a Horizon Europe opportunity for you.
Explore the Full List of Cluster 1 – Health Topics:
✔ Staying healthy in a rapidly changing society;
✔ Living and working in a health-promoting environment;
✔ Tackling diseases and reducing disease burden;
✔ Developing and using new tools, technologies and digital solutions for a healthy society;
✔ Maintaining an innovative, sustainable, and competitive EU health industry;
✔ Ensuring equal access to innovative, sustainable, and high-quality healthcare.
These topics reflect Europe's commitment to a more resilient, equitable, and digitally empowered healthcare system.
Topics | Type | Budget (EUR million) |
Budget/ project |
Number of projects expected to be funded |
Deadline |
---|---|---|---|---|---|
Destination - Tackling diseases and reducing disease burden | |||||
HORIZON-HLTH-2025-01-DISEASE-01: Testing safety and efficacy of phage therapy for the treatment of antibiotic-resistant bacterial infections | RIA | 45.00 | 15.00 | 3 | 16 Sep 2025 |
HORIZON-HLTH-2025-01-DISEASE-03: Development of antibodies and antibody-derived proteins for the prevention and treatment of infectious diseases with epidemic potential | RIA | 50.00 | 10.00 | 5 | 16 Sep 2025 |
HORIZON-HLTH-2025-01-DISEASE-04: Leveraging artificial intelligence for pandemic preparedness and response | RIA | 35.00 | 6.00 to 8.00 | 5 | 16 Sep 2025 |
HORIZON-HLTH-2025-01-DISEASE-05: Support for the functioning of the Global Research Collaboration for Infectious Disease Preparedness (GloPID-R) | CSA | 2.00 | 2.00 | 1 | 16 Sep 2025 |
HORIZON-HLTH-2025-01-DISEASE-06: Implementation research addressing strategies to strengthen health systems for equitable high quality care and health outcomes in the context of non-communicable diseases (GACD) | RIA | 20.00 | 3.00 to 4.00 | 5 | 16 Sep 2025 |
HORIZON-HLTH-2025-01-DISEASE-07: Tackling high-burden for patients and under researched medical conditions | RIA | 30.00 | 6.00 | 5 | 16 Sep 2025 |
HORIZON-HLTH-2025-03-DISEASE-02-two-stage: Advancing innovative interventions for mental, behavioural and neurodevelopmental disorders | RIA | 50.00 | 6.00 to 8.00 | 7 | 16 Sep 2025 (stage 1) |
Destination - Ensuring equal access to innovative, sustainable, and high-quality healthcare | |||||
HORIZON-HLTH-2025-01-CARE-01: End user-driven application of Generative Artificial Intelligence models in healthcare (GenAI4EU) | RIA | 40.00 | 15.00 to 20.00 | 2 | 16 Sep 2025 |
Developing and using new tools, technologies and digital solutions for a healthy society | |||||
HORIZON-HLTH-2025-01-TOOL-01: Enhancing cell therapies with genomic techniques | RIA | 50.00 | 8.00 to 10.00 | 5 | 16 Sep 2025 |
HORIZON-HLTH-2025-01-TOOL-02: Advancing cell secretome-based therapies | RIA | 40.00 | 9.00 to 13.00 | 3 | 16 Sep 2025 |
HORIZON-HLTH-2025-01-TOOL-03: Leveraging multimodal data to advance Generative Artificial Intelligence applicability in biomedical research (GenAI4EU) | RIA | 50.00 | 15.00 to 17.00 | 3 | 16 Sep 2025 |
HORIZON-HLTH-2025-01-TOOL-05: Boosting the translation of biotech research into innovative health therapies | RIA | 80.00 | 4.00 to 8.00 | 10 | 16 Sep 2025 |
Destination - Maintaining an innovative, sustainable, and competitive EU health industry | |||||
HORIZON-HLTH-2025-01-IND-01: Optimising the manufacturing of Advanced Therapy Medicinal Products (ATMPs) | IA | 40.00 | 6.00 to 8.00 | 5 | 16 Sep 2025 |
HORIZON-HLTH-2025-01-IND-02: Digitalisation of conformity assessment procedures of medical devices and in vitro diagnostic medical devices | CSA | 4.00 | 4.00 | 1 | 16 Sep 2025 |
HORIZON-HLTH-2025-03-IND-03-two-stage: Facilitating the conduct of multinational clinical studies of orphan devices and/or of highly innovative (“breakthrough”) devices | RIA | 40.00 | 6.00 to 8.00 | 5 | 16 Sep 2025 (stage 1) |
Destination - Staying healthy in a rapidly changing society | |||||
HORIZON-HLTH-2025-03-STAYHLTH-01-two-stage: Improving the quality of life of persons with intellectual disabilities and their families | RIA | 40.00 | 6.00 to 8.00 | 5 | 16 Sep 2025 (stage 1) |
Destination - Living and working in a health-promoting environment | |||||
HORIZON-HLTH-2025-03-ENVHLTH-01-two-stage: The impact of pollution on the development and progression of brain diseases and disorders | RIA | 40.00 | 6.00 to 7.00 | 6 | 16 Sep 2025 (stage 1) |
HORIZON-HLTH-2025-03-ENVHLTH-02-two-stage: Advancing knowledge on the impacts of micro- and nanoplastics on human health | RIA | 40.00 | 7.00 to 8.00 | 5 | 16 Sep 2025 (stage 1) |
We’re also highlighting a selection of transformative topics from Cluster 6, focused on:
🌱 Investments in transformative innovations;
♻️ Achieving a circular economy and zero pollution;
🌿 Restoring European biodiversity.
Short selection of transformative topics from Cluster 6
Topic | Type | Budget (EUR million) |
Budget/ project |
Number of projects expected to be funded |
Deadline |
---|---|---|---|---|---|
Destination - Fair, healthy and environment-friendly food systems from primary production to consumption | |||||
HORIZON CL6-2025-02-FARM2FORK-02: Additional activities for the European partnership on animal health and welfare | COFUND | 120.00 | 120.00 | 1 | 16 Sept 2025 |
HORIZON-CL6-2025-02-FARM2FORK-03-two-stage: Making food systems more resilient to food safety risks through the deployment of technological solutions | IA | 12.00 | 6.00 | 2 | 04 Sept 2025 (stage 1) |
Destination - Clean environment and zero pollution | |||||
HORIZON-CL6-2025-01-ZEROPOLLUTION-04: Towards a comprehensive European strategy to assess and monitor aquatic litter including plastic and microplastic pollution | RIA | 6.00 | 6.00 | 1 | 17 Sept 2025 |
HORIZON-CL6-2025-01-ZEROPOLLUTION-05: EU-India cooperation on cumulative impacts of marine pollution on marine organisms and ecosystems | RIA | 12.00 | 6.00 | 2 | 17 Sept 2025 |
HORIZON-CL6-2025-01-ZEROPOLLUTION-07: Reducing pollution from the food and drink industries | IA | 12.00 | 6.00 | 2 | 17 Sept 2025 |
Destination - Land, ocean and water for climate action | |||||
HORIZON-CL6-2025-02-CLIMATE-03: Understanding and managing medium and longer-term challenges and opportunities for agriculture stemming from shifting climatic zones and changing agroecological environments | RIA | 10.00 | 5.00 | 2 | 16 Sept 2025 |
HORIZON-CL6-2025-02-FARM2FORK-04: Enhancing plant protein production to bolster the resilience of agricultural systems and EU self-sufficiency in plant protein used as feed | RIA | 11.00 | 5.50 | 2 | 16 Sept 2025 |
HORIZON-CL6-2025-02-FARM2FORK-07: Fostering animal breeding and genetics for climate change adaptation and mitigation, improved robustness and resilience | RIA | 12.00 | 6.00 | 2 | 16 Sept 2025 |
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