Horizon Europe calls 2026 preview




Cluster 1 “Health”

These calls will support ambitious, collaborative projects that tackle Europe's most pressing health challenges. With a wide range of topics across key Destinations, there's a wealth of opportunities for researchers, innovators, and stakeholders across the health ecosystem. Whether your work addresses prevention, diagnosis, treatment, or healthcare delivery, there’s a Horizon Europe opportunity for you.


Explore the Full List of Cluster 1 – Health Topics:

  Staying healthy in a rapidly changing society;
  Living and working in a health-promoting environment;
  Tackling diseases and reducing disease burden;
  Developing and using new tools, technologies and digital solutions for a healthy society;
  Maintaining an innovative, sustainable, and competitive EU health industry;
  Ensuring equal access to innovative, sustainable, and high-quality healthcare.

These topics reflect Europe's commitment to a more resilient, equitable, and digitally empowered healthcare system.
Download the DRAFT WorkProgramme
HORIZON-CL1-2026-2027_06_20_2025_V3-DRAFT.pdf

Topics Type Budget
(EUR million)
Budget/
project
Number of
projects expected
to be funded
Deadline
Destination - Staying healthy in a rapidly changing society
HORIZON-HLTH-2026-01-STAYHLTH-02: Behavioural interventions as primary prevention for Non-Communicable Diseases (NCDs) among young people RIA 21.00 9.00 to 10.00 2 16 Apr 2026
Destination - Living and working in a health-promoting environment
HORIZON-HLTH-2026-01-ENVHLTH-01: Towards a better understanding and anticipation of the impacts of climate change on health RIA 55.00 7.00 to 8.00 7 16 Apr 2026
HORIZON-HLTH-2026-01-ENVHLTH-04: Towards climate resilient, prepared and carbon neutral populations and healthcare systems RIA 50.00 7.00 to 8.00 7 16 Apr 2026
HORIZON-HLTH-2026-01-ENVHLTH-05: Support for a multilateral initiative on climate change and health research CSA 3.00 Around 3.00 1 16 Apr 2026
Destination - Tackling diseases and reducing disease burden
HORIZON-HLTH-2026-01-DISEASE-02: Innovative interventions to prevent the harmful effects of using digital technologies on the mental health of children and young adults RIA 45.00 Around 8.00 6 16 Apr 2026
HORIZON-HLTH-2026-01-DISEASE-03: Advancing research on the prevention, diagnosis, and management of post-infection long-term conditions RIA 40.00 6.00 to 8.00 5 16 Apr 2026
HORIZON-HLTH-2026-01-DISEASE-04: Development of novel vaccines for viral pathogens with epidemic potential RIA 45.00 Around 10.00 5 16 Apr 2026
HORIZON-HLTH-2026-01-DISEASE-09: Multisectoral approach to tackle chronic non-communicable diseases: implementation research maximising collaboration and coordination with sectors and in settings beyond the healthcare system (GACD) RIA 12.00 3.00 to 4.00 3 16 Apr 2026
HORIZON-HLTH-2026-01-DISEASE-11: Understanding of sex and/or gender-specific mechanisms of cardiovascular diseases: determinants, risk factors and pathways RIA 40.00 6.00 to 7.00 6 16 Apr 2026
HORIZON-HLTH-2026-01-DISEASE-15: Scaling up innovation in cardiovascular health CSA 2.00 Around 2.00 1 16 Apr 2026
Destination - Ensuring equal access to innovative, sustainable, and high-quality healthcare
HORIZON-HLTH-2026-01-CARE-01: Public procurement of innovative solutions for improving citizens' access to healthcare through integrated and personalised approaches PPI 25.00 3.00 to 8.00 4 16 Apr 2026
HORIZON-HLTH-2026-01-CARE-03: Identifying and addressing low-value care in health and care systems RIA 45.00 Around 10.00 5 16 Apr 2026
HORIZON-HLTH-2026-04-CARE-04: Enhancing and enlarging the European Partnership on Personalised Medicine (EP PerMEd) (Top-up) COFUND 15.00 Around 15.00 1 16 Apr 2026
Destination - Developing and using new tools, technologies and digital solutions for a healthy society
HORIZON-HLTH-2026-01-TOOL-03: Integrating New Approach Methodologies (NAMs) to advance biomedical research and regulatory testing RIA 50.00 5.00 to 8.00 7 16 Apr 2026
HORIZON-HLTH-2026-01-TOOL-06: Support to European Research Area (ERA) action on accelerating New Approach Methodologies (NAMs) to advance biomedical research and testing of medicinal products and medical devices CSA 3.00 Around 3.00 1 16 Apr 2026
Destination - Maintaining an innovative, sustainable, and competitive EU health industry
HORIZON-HLTH-2026-01-IND-03: Regulatory science to support translational development of patient-centred health technologies RIA 20.00 4.00 to 6.00 4 16 Apr 2026

Mission Cancer

The goal of the Mission on Cancer is to improve the lives of more than 3 million people by 2030, through prevention, cure and for those affected by cancer including their families, to live longer and better.


The four Cancer Mission objectives are:

  Understand;
  Prevent what is preventable;
  Optimise diagnosis and treatment;
  Support quality of life.

Its five transversal priorities are: ensure equitable access in all aforementioned areas, innovation, childhood cancer, personalised medicine and citizen engagement.


Explore the Full List of Mission Cancer – Topics:
Download the DRAFT WorkPlan
HORIZON-MISS-2026-2027_07_04_2025-DRAFT.pdf

Topics Type Budget
(EUR million)
Budget/
project
Number of
projects expected
to be funded
Deadline
Cancer: Supporting the implementation of the Cancer Mission
HORIZON-MISS-2026-02-CANCER-01: Virtual Human Twin (VHT) Models for Cancer Research RIA 35.00 8.00 to 9.00 4 15 Sep 2026
HORIZON-MISS-2026-02-CANCER-02: Microbiome for early cancer prediction before the onset of disease RIA 15.00 Around 15.00 1 15 Sep 2026
HORIZON-MISS-2026-02-CANCER-03: Pragmatic clinical trials to optimise immunotherapeutic interventions for patients with refractory cancers RIA 22.20 6.00 to 9.00 3 15 Sep 2026
HORIZON-MISS-2026-02-CANCER-04: Earlier and more precise palliative care RIA 15.00 Around 5.00 3 15 Sep 2026
HORIZON-MISS-2026-02-CANCER-05: Boosting mental health of young cancer survivors through the European Cancer Patient Digital Centre (ECPDC) IA 7.00 Around 7.00 1 15 Sep 2026
HORIZON-MISS-2026-02-CANCER-06: Development of a research capacity building programme on cancer with and for Ukraine CSA 5.00 Around 5.00 1 15 Sep 2026
HORIZON-MISS-2026-02-CANCER-07: Improve the Quality of Life of older cancer patients RIA 27.00 5.00 to 6.00 5 15 Sep 2026

Spotlight on Cluster 6 – Food, Bioeconomy, Natural Resources, Agriculture and Environment

We’re also highlighting a selection of transformative topics from Cluster 6, focused on:

🌿 Biodiversity and ecosystem services (BIODIV);

♻️ Circular economy and bioeconomy sectors (CIRBIO);
♻️ Clean environment and zero pollution (ZEROPOULLTION);
🌱 Fair, healthy and environment-friendly food systems from primary production to consumption (FARM2FORK).

These calls are essential for shaping a healthier, greener, and more sustainable Europe. Don’t miss your chance to be part of the change!
Download the DRAFT WorkProgramme
HORIZON-CL6-2026-2027_07_30_2025_ISC-draft_version-clean.pdf

Topics Type Budget
(EUR million)
Budget/
project
Number of
projects expected
to be funded
Deadline
Destination - Biodiversity and ecosystem services
HORIZON-CL6-2026-01-BIODIV-01: Understanding and tackling the decline of insects RIA 13.00 6.50 2 17 Sep 2026
HORIZON-CL6-2026-01-BIODIV-02: Developing methods to assess the presence, functions and sensitivity of groundwater ecosystems RIA 10.00 5.00 2 17 Sep 2026
HORIZON-CL6-2026-01-BIODIV-06: Boosting agrobiodiversity for food security and sustainable competitiveness RIA 10.00 5.00 2 17 Sep 2026
Destination - Circular economy and bioeconomy sectors
HORIZON-CL6-2026-01-CIRCBIO-01: Improving circularity of multilayer flexible plastic food contact packaging IA 11.00 5.00 to 6.00 2 17 Sep 2026
HORIZON-CL6-2026-01-CIRCBIO-07: Advancing the European bio-based innovation enabled by biotechnology and biomanufacturing concepts RIA 12.00 4.00 3 17 Sep 2026
HORIZON-CL6-2026-01-CIRCBIO-09: Balancing food security, bioeconomy, climate and biodiversity objectives while unlocking sustainable value chains RIA 12.00 6.00 2 17 Sep 2026
Destination - Clean environment and zero pollution
HORIZON-CL6-2026-01-ZEROPOLLUTION-01: Toward a comprehensive assessment of the disturbance of marine ecosystems by anthropogenic underwater noise RIA 10.00 10.00 1 17 Sep 2026
HORIZON-CL6-2026-01-ZEROPOLLUTION-02: Bioremediation of Ukraine’s ecosystems contaminated by conflicts IA 11.00 5.00 to 6.00 2 17 Sep 2026
HORIZON-CL6-2026-01-ZEROPOLLUTION-03: Developing managed aquifer recharge techniques (MAR) in a rural context RIA 12.00 6.00 2 17 Sep 2026
Destination - Fair, healthy and environment-friendly food systems from primary production to consumption
HORIZON-CL6-2026-02-FARM2FORK-05: Boosting circularity and diversification strategies of terrestrial livestock production systems RIA 12.00 6.00 2 14 Apr 2026
HORIZON-CL6-2026-02-FARM2FORK-07: Strengthening the EU plant protection ecosystem for a future-proof agriculture CSA 3.00 3.00 1 14 Apr 2026
HORIZON-CL6-2026-02-FARM2FORK-09: Sustainable and healthy diets for cardiovascular diseases prevention with the support of digital applications IA 12.00 Around 6.00 2 14 Apr 2026
HORIZON-CL6-2026-02-FARM2FORK-11: Integrating a holistic perspective in microbiome research for resilient, competitive and sustainable food systems RIA 11.00 5.00 to 6.00 2 14 Apr 2026
Two-Stage Calls 2026
HORIZON-CL6-2026-01-BIODIV-02-two-stage: Open topic: Uncovering the causes of specific species’ rapid decline and exploring actionable solutions RIA 12.00 3.00 4 16 Apr 2026 (First Stage), 23 Sep 2026 (Second Stage)
HORIZON-CL6-2026-02-FARM2FORK-01-two-stage: Open topic: Improving the competitiveness of the agricultural sector by enhancing the efficient and sustainable use of agricultural production factors IA 13.50 4.50 3 14 Apr 2026 (First Stage), 15 Sep 2026 (Second Stage)
HORIZON-CL6-2026-02-FARM2FORK-02-two-stage: Open topic: Boosting organic farming for a competitive, sustainable and resilient farming sector IA 13.50 4.50 3 14 Apr 2026 (First Stage), 15 Sep 2026 (Second Stage)

EIC Pathfinder

EIC Pathfinder is part of the European Innovation Council (EIC), designed to fund early-stage, high-risk / high-gain research that can pave the way to breakthrough technologies.
Within Pathfinder, the Open call is the “bottom-up” strand: it welcomes proposals in any field of science, technology or application, without predefined thematic priorities.
The 2026 Challenges Call includes three cutting-edge thematic strands that seek to push the frontiers of science and enable transformative technology development:

  • II.2.1 Advanced Materials for Miniaturised Energy Harvesting Systems — This topic invites proposals to develop novel materials and device architectures that can efficiently scavenge ambient energy at microscale. The ambition is to enable self-powered miniaturised systems (e.g. IoT devices, sensors, wearable electronics) through breakthroughs in material properties, integration strategies, and energy conversion techniques.
  • II.2.2 Biotechnology for Healthy Ageing — This theme focuses on leveraging biotechnology, bioengineering and life-science innovations to promote longer, healthier lifespans. It aims to address biological aging processes, preventative diagnostics, regenerative therapies, and interventions that maintain functional resilience over time.
  • II.2.3 DeepRAP: Deep Reasoning, Abstraction & Planning towards Trustworthy Cognitive AI Systems — Under this call, the goal is to advance the methodological foundations of AI by combining deep learning with symbolic reasoning, abstraction, planning and verification. The ambition is to build more trustworthy, interpretable, and robust cognitive systems that can operate reliably in complex, uncertain environments.
EIC Pathfinder targets work in the earliest Technology Readiness Levels (TRLs), typically TRL 1 to TRL 4 — i.e. from basic research up to proof-of-concept / lab validation.

Download the DRAFT WorkProgramme
EIC-Work-Programme-2026_thirddraft_ISC_170725.pdf

Topics Type Budget
(EUR million)
Budget/
project
Number of
projects expected
to be funded
Deadline
Pathfinder OPEN 166 4 41 06 May 2026
Pathfinder CHALLENGES 96 4 24 28 October 2026

   


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