Cluster 6 - Food, Bioeconomy, Natural Resources, Agriculture and Environment
These calls help deliver sustainable food systems, protect biodiversity, and drive circular bioeconomy approaches. Spanning agriculture, ecosystems, and natural resources, this cluster offers rich opportunities for researchers and innovators building a greener, more resource-efficient Europe.
Focus: Ensuring sustainability and resilience of food systems and ecosystems.
Key areas:
- Biodiversity and ecosystem services
- Sustainable agriculture, forestry, and fisheries
- Circular bioeconomy
- Food systems and security
- Water and soil management
Open Calls
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Cluster 5 - Climate, Energy & Mobility
These calls support forward-looking collaborations tackling climate change and accelerating the green transition. Opportunities cover clean energy systems, sustainable mobility, and climate adaptation. Whether your work advances low-carbon solutions, smart transport, or resilience strategies, this cluster provides a strong platform for impact.
Focus: Achieving climate neutrality and sustainable transport and energy systems.
Key areas:
- Climate science and solutions
- Energy systems and grids
- Renewable energy
- Smart and sustainable mobility
- Energy efficiency and storage
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Cluster 4 - Digital, Industry & Space
These calls empower cutting-edge projects shaping Europe’s digital transformation, industrial leadership, and space innovation. With topics ranging from advanced manufacturing to AI and next-generation space systems, this cluster offers exciting possibilities for innovators driving Europe’s technological future.
Focus: Driving digital and industrial transformation and ensuring technological sovereignty.
Key areas:
- Advanced manufacturing and materials
- Artificial intelligence, data, and robotics
- Microelectronics and photonics
- Space technologies and applications
- Circular and low-carbon industry
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Cluster 3 - Civil Security for Society
These calls back ambitious partnerships that enhance Europe’s security and resilience. From disaster preparedness to cybersecurity and crime prevention, opportunities span a wide range of priorities. Whether you work on technologies, policies, or cross-sector strategies, there’s a Horizon Europe pathway to boost societal safety.
Focus: Protecting citizens from crime, terrorism, and disasters.
Key areas:
- Disaster-resilient societies
- Protection and security
- Cybersecurity
- Border management
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Cluster 2 - Culture, Creativity & Inclusive Society
These calls support collaborative projects that strengthen democratic governance, foster cultural and creative innovation, and promote social inclusion. With diverse topics across key Destinations, researchers and stakeholders can advance understanding, drive societal change, and help build resilient, inclusive European communities.
Focus: Strengthening democratic governance, social cohesion, and cultural heritage.
Key areas:
- Democracy and governance
- Cultural heritage and creative industries
- Social and economic transformations
- Migration, identity, and inclusion
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Cluster 1 - Health
These calls will support ambitious, collaborative projects that tackle Europe’s most pressing health challenges. With a wide range of topics across key Destinations, there’s a wealth of opportunities for researchers, innovators, and stakeholders across the health ecosystem. Whether your work addresses prevention, diagnosis, treatment, or healthcare delivery, there’s a Horizon Europe opportunity for you.
Explore the Full List of Cluster 1 – Health Topics:
- Staying healthy in a rapidly changing society
- Living and working in a health-promoting environment
- Tackling diseases and reducing disease burden
- Developing and using new tools, technologies and digital solutions for a healthy society
- Maintaining an innovative, sustainable, and competitive EU health industry
- Ensuring equal access to innovative, sustainable, and high-quality healthcare
These topics reflect Europe’s commitment to a more resilient, equitable, and digitally empowered healthcare system.
Open Calls
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ERDERA
Multinational research teams are invited to apply for ERDERA’s 2026 call focused on providing diagnostic clarity for unsolved rare genetic and nongenetic diseases. The call aims to close these gaps and deliver actionable diagnostic evidence for patients and families. Read more at this LINK.
Open Calls
Deadline for pre-proposal submission - 12 February 2026
Deadline for full proposal submission - 08 July 2026
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EP PerMed
The European Partnership for Personalised Medicine (EP PerMed) is a Horizon Europe-funded initiative (launched in Nov 2023) that coordinates research, innovation, and implementation across Europe to accelerate personalised medicine. It brings together national/regional funding bodies, ministries, healthcare providers, industry, researchers, and patients to support the full “value continuum” — from basic research to clinical pilots and health system uptake.
Key goals include:
- Translating scientific discoveries into patient-centred applications
- Integrating big data, digital health, and omics technologies
- Strengthening health systems’ capacity to adopt personalised approaches
- Demonstrating the value (clinical, societal, economic) of personalised medicine for sustainable healthcare
To steer its work, EP PerMed follows a Strategic Research & Innovation Agenda (SRIA) that defines priorities and supports joint calls, pilot projects, capacity building, and policy dialogue.
Open Calls
Call Announcement - Research, Innovation and Technology Call for Proposals (RITC) 2026
Call Title: Test and Demonstration of Multimodal Data Approaches for Personalised Medicine (MultiPMData2026). Call Text Link
EP PerMed will fund innovation projects in human health that focus on multimodal data usage for PM approaches aiming to provide more efficient and personalised management of patients with multimorbidity, having at least two chronic diseases that require management and adhere to the definition.
19 funding organizations participate in this call with an available budget of over 14.8 Mio. € (approx.). They have agreed to jointly fund multinational innovative research and technology projects in personalized medicine (PM) to encourage innovative, interdisciplinary public-private partnerships and to support the translational and clinical implementation of research outcomes.
The call will be implemented in two stages, i.e. a pre- and a full proposal phase.
Deadline for pre-proposal submission - 12 January 2026 (14:00, CET)
Deadline for full-proposal submission - 27 April 2026 (14:00, CEST)
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IHI
The Innovative Health Initiative (IHI) is a European Partnership under Horizon Europe, funded jointly by the European Union via HE and by health industry partners.
The Innovative Health Initiative (IHI) is a large-scale public–private partnership that brings together the EU and health industry stakeholders to accelerate the development of innovative healthcare solutions. It funds collaborative, cross-sector projects that tackle complex challenges—spanning medicines, medical technologies, digital health, and patient care. By fostering collaboration between academia, industry, SMEs, and patient organisations, IHI aims to deliver more integrated, sustainable, and patient-centred innovations for Europe’s health systems.
Open Calls:
https://www.ihi.europa.eu/news-events/newsroom/just-published-draft-text-ihi-call-12 .
IHI Call 12 will be a single-stage, applicant-driven call with five topics – each one linked to the five key objectives in our Strategic Research and Innovation Agenda (SRIA).
- Topic 1: Boosting innovation for a better understanding of the determinants of health
- Topic 2: Boosting innovation through better integration of fragmented health R&I efforts
- Topic 3: Boosting innovation for people-centred integrated healthcare solutions
- Topic 4: Boosting innovation through exploitation of digitalisation and data exchange in healthcare
- Topic 5: Boosting innovation for better assessment of the added value of innovative integrated healthcare solutions
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Mission Cancer
Horizon Europe Missions are a new programming approach under Pillar II – Global Challenges and European Industrial Competitiveness, designed with a horizontal, inter-cluster structure. They tackle major social and environmental challenges through bold, measurable objectives to be achieved within clear timelines. By mobilizing researchers, businesses, policymakers, and citizens, the Missions aim to accelerate innovation and deliver tangible benefits in areas such as climate adaptation, cancer, oceans, soil health, and climate-neutral cities.
Mission Cancer
The goal of the Mission on Cancer is to improve the lives of more than 3 million people by 2030, through prevention, cure and for those affected by cancer including their families, to live longer and better.
The four Cancer Mission objectives are:
✔ Understand;
✔ Prevent what is preventable;
✔ Optimise diagnosis and treatment;
✔ Support quality of life.
Its five transversal priorities are: ensure equitable access in all aforementioned areas, innovation, childhood cancer, personalised medicine and citizen engagement.
Open Calls