Cluster 4 - Digital, Industry & Space
These calls empower cutting-edge projects shaping Europe’s digital transformation, industrial leadership, and space innovation. With topics ranging from advanced manufacturing to AI and next-generation space systems, this cluster offers exciting possibilities for innovators driving Europe’s technological future.
Focus: Driving digital and industrial transformation and ensuring technological sovereignty.
Key areas:
- Advanced manufacturing and materials
- Artificial intelligence, data, and robotics
- Microelectronics and photonics
- Space technologies and applications
- Circular and low-carbon industry
Cluster 3 - Civil Security for Society
These calls back ambitious partnerships that enhance Europe’s security and resilience. From disaster preparedness to cybersecurity and crime prevention, opportunities span a wide range of priorities. Whether you work on technologies, policies, or cross-sector strategies, there’s a Horizon Europe pathway to boost societal safety.
Focus: Protecting citizens from crime, terrorism, and disasters.
Key areas:
- Disaster-resilient societies
- Protection and security
- Cybersecurity
- Border management
Cluster 2 - Culture, Creativity & Inclusive Society
These calls support collaborative projects that strengthen democratic governance, foster cultural and creative innovation, and promote social inclusion. With diverse topics across key Destinations, researchers and stakeholders can advance understanding, drive societal change, and help build resilient, inclusive European communities.
Focus: Strengthening democratic governance, social cohesion, and cultural heritage.
Key areas:
- Democracy and governance
- Cultural heritage and creative industries
- Social and economic transformations
- Migration, identity, and inclusion
Cluster 1 - Health
These calls will support ambitious, collaborative projects that tackle Europe’s most pressing health challenges. With a wide range of topics across key Destinations, there’s a wealth of opportunities for researchers, innovators, and stakeholders across the health ecosystem. Whether your work addresses prevention, diagnosis, treatment, or healthcare delivery, there’s a Horizon Europe opportunity for you.
Explore the Full List of Cluster 1 – Health Topics:
- Staying healthy in a rapidly changing society
- Living and working in a health-promoting environment
- Tackling diseases and reducing disease burden
- Developing and using new tools, technologies and digital solutions for a healthy society
- Maintaining an innovative, sustainable, and competitive EU health industry
- Ensuring equal access to innovative, sustainable, and high-quality healthcare
These topics reflect Europe’s commitment to a more resilient, equitable, and digitally empowered healthcare system.
Open Calls
| Topics | Type | Budget (EUR million) 2026 |
Budget
(EUR million) 2027 |
Projects expected to be funded | Deadline |
| HORIZON-HLTH-2026-02DISEASE-12: European Partnership on Rare Diseases (ERDERA) (Phase 2) | COFUND | 48.70 | 42.60 | 1 | 15 Sep 2026 |
ERDERA
Multinational research teams are invited to apply for ERDERA’s 2026 call focused on providing diagnostic clarity for unsolved rare genetic and nongenetic diseases. The call aims to close these gaps and deliver actionable diagnostic evidence for patients and families. Read more at this LINK.
Open Calls
Deadline for pre-proposal submission - 12 February 2026
Deadline for full proposal submission - 08 July 2026
EP PerMed
The European Partnership for Personalised Medicine (EP PerMed) is a Horizon Europe-funded initiative (launched in Nov 2023) that coordinates research, innovation, and implementation across Europe to accelerate personalised medicine. It brings together national/regional funding bodies, ministries, healthcare providers, industry, researchers, and patients to support the full “value continuum” — from basic research to clinical pilots and health system uptake.
Key goals include:
- Translating scientific discoveries into patient-centred applications
- Integrating big data, digital health, and omics technologies
- Strengthening health systems’ capacity to adopt personalised approaches
- Demonstrating the value (clinical, societal, economic) of personalised medicine for sustainable healthcare
To steer its work, EP PerMed follows a Strategic Research & Innovation Agenda (SRIA) that defines priorities and supports joint calls, pilot projects, capacity building, and policy dialogue.
Open Calls
no updates
IHI
The Innovative Health Initiative (IHI) is a European Partnership under Horizon Europe, funded jointly by the European Union via HE and by health industry partners.
The Innovative Health Initiative (IHI) is a large-scale public–private partnership that brings together the EU and health industry stakeholders to accelerate the development of innovative healthcare solutions. It funds collaborative, cross-sector projects that tackle complex challenges—spanning medicines, medical technologies, digital health, and patient care. By fostering collaboration between academia, industry, SMEs, and patient organisations, IHI aims to deliver more integrated, sustainable, and patient-centred innovations for Europe’s health systems.
Open Calls:
The Innovative Health Initiative (IHI) Draft topics for upcoming Innovative Health Initiative (IHI) calls are now available, with updates expected in early June. If you are planning to apply, registration for the IHI Call Days is now open — a key opportunity to learn more about the calls, funding priorities and application process. IHI is also offering training and masterclasses on its “Field Manual for Scaling Innovation” to help projects turn research results into real-world impact.
The IHI Call Days for IHI call 13 will take place from 24 to 30 June online and will include sessions on the individual topics as well as the rules and procedures. It will spotlight some of the most pressing challenges and opportunities in health innovation, from advancing immuno-science in age-related diseases to exploring the future of AI-driven toxicology models for safer drug development.
Sessions will also cover the launch of the European healthcare incubator network and provide practical guidance on the rules and procedures for two-stage calls, helping applicants navigate upcoming funding opportunities and collaborative research initiatives – Register here
Mission Cancer
Horizon Europe Missions are a new programming approach under Pillar II – Global Challenges and European Industrial Competitiveness, designed with a horizontal, inter-cluster structure. They tackle major social and environmental challenges through bold, measurable objectives to be achieved within clear timelines. By mobilizing researchers, businesses, policymakers, and citizens, the Missions aim to accelerate innovation and deliver tangible benefits in areas such as climate adaptation, cancer, oceans, soil health, and climate-neutral cities.
Mission Cancer
The goal of the Mission on Cancer is to improve the lives of more than 3 million people by 2030, through prevention, cure and for those affected by cancer including their families, to live longer and better.
The four Cancer Mission objectives are:
✔ Understand;
✔ Prevent what is preventable;
✔ Optimise diagnosis and treatment;
✔ Support quality of life.
Its five transversal priorities are: ensure equitable access in all aforementioned areas, innovation, childhood cancer, personalised medicine and citizen engagement.
Open Calls
EU4Health
The EU4Health Programme is the EU’s dedicated health funding instrument for 2021–2027, created to strengthen Europe’s resilience to health crises and improve public health across member states. It supports actions that enhance disease prevention, reinforce health systems, improve access to medicines and medical devices, and boost cooperation at EU level. Through targeted funding, EU4Health aims to build a healthier, more prepared, and more equitable Europe.
The EU4Health Programme is managed by DG SANTE (European Commission).
Open Calls
Multiple sourcing Framework Contracts to speed up the development of and access to innovative medical countermeasures Next Generation Therapeutics for Infectious Diseases.
Read more here LINK
Clinical Trial Readiness through the Establishment of a Pilot Filovirus Investigational Vaccine Reserve.
Read more here: LINK
The project aims to establish and maintain a European stockpile of experimental vaccines that can be quickly used during outbreaks and incorporated into emergency clinical studies. This strategy is intended to speed up vaccine clinical development beginning at Phase 2.
Deadline: 02 September 2026
Long-term stockpiling of active pharmaceutical ingredients (APIs) and rapid production of finished dose forms.
Read more here: LINK
The objective is to evaluate technologies capable of extending the shelf life of APIs, enabling flexible and rapid production in the event of health emergencies, improving the sustainability and resilience of healthcare systems
Deadline: 30 September 2026
MSCA Doctoral Networks
The Marie Skłodowska-Curie Actions (MSCA) support excellent research training, skills development, and international mobility for researchers at all career stages. Trough its main calls—Doctoral Networks, Postdoctoral Fellowships, Staff Exchanges, COFUND, and MSCA and Citizens—the programme strengthens Europe’s research landscape by fostering international collaboration, interdisciplinary learning, and the growth of highly skilled, globally connected researchers.
Doctoral Networks are a key component, funding international, interdisciplinary, and intersectoral doctoral programmes. They help institutions attract top talent, provide high-quality supervision, and equip PhD candidates with advanced scientific and transferable skills, preparing them for successful careers within and beyond academia.
The goal of MSCA Postdoctoral Fellowships is to enhance the creative and innovative potential of researchers holding a PhD and who wish to acquire new skills through advanced training, international, inter-sectoral and interdisciplinary mobility. MSCA Postdoctoral Fellowships will be open to excellent researchers of any nationality.
Open Calls
Postdoctoral fellowships
| Topic | Type of Action | Budget (EUR million) |
Deadline |
| HORIZON-MSCA2026-PF-01-01 | TMA Postdoctoral Fellowships – European Fellowships | 339.19 | 09 Sep 2026 |
| HORIZON-MSCA2026-PF-01-01 | TMA Postdoctoral Fellowships – Global Fellowships | 59.86 | 09 Sep 2026 |
Doctoral Networks
| Topic | Type of Action | Budget (EUR million) |
Deadline |
| HORIZON-MSCA2026-DN-01-01 | TMA Doctoral Networks | 593.03 | 24 November 2026 |
| HORIZON-MSCA2026-DN-01-01 | TMA Doctoral Networks – Industrial Doctorates | 24 November 2026 | |
| HORIZON-MSCA2026-DN-01-01 | TMA Doctoral Networks – Joint Doctorates | 24 November 2026 |