Horizon Europe Work programme (2026-27) - Cluster 1

These calls will support ambitious, collaborative projects that tackle Europe’s most pressing health challenges. With a wide range of topics across key Destinations, there’s a wealth of opportunities for researchers, innovators, and stakeholders across the health ecosystem. Whether your work addresses prevention, diagnosis, treatment, or healthcare delivery, there’s a Horizon Europe opportunity for you.

Explore the Full List of Cluster 1 – Health Topics:

  • Staying healthy in a rapidly changing society
  • Living and working in a health-promoting environment
  • Tackling diseases and reducing disease burden
  • Developing and using new tools, technologies and digital solutions for a healthy society
  • Maintaining an innovative, sustainable, and competitive EU health industry
  • Ensuring equal access to innovative, sustainable, and high-quality healthcare

These topics reflect Europe’s commitment to a more resilient, equitable, and digitally empowered healthcare system.

Open Calls

Topics Type Budget
(EUR million)		 Budget/
project		 Projects expected to be funded Deadline

 

Destination – Staying healthy in a rapidly changing society
HORIZON-HLTH-2026-01-STAYHLTH-02: Behavioural interventions as primary prevention for Non-Communicable Diseases (NCDs) among young people RIA 21.00 9.00 to 10.00 2 16 Apr 2026
Destination – Living and working in a health-promoting environment
HORIZON-HLTH-2026-01-ENVHLTH-01: Towards a better understanding and anticipation of the impacts of climate change on health RIA 55.00 7.00 to 8.00 7 16 Apr 2026
HORIZON-HLTH-2026-01-ENVHLTH-04: Towards climate resilient, prepared and carbon neutral populations and healthcare systems RIA 50.00 7.00 to 8.00 7 16 Apr 2026
HORIZON-HLTH-2026-01-ENVHLTH-05: Support for a multilateral initiative on climate change and health research CSA 3.00 Around 3.00 1 16 Apr 2026

 

Destination – Tackling diseases and reducing disease burden
HORIZON-HLTH-2026-01-DISEASE-02: Innovative interventions to prevent the harmful effects of using digital technologies on the mental health of children and young adults RIA 45.00 Around 8.00 6 16 Apr 2026
HORIZON-HLTH-2026-01-DISEASE-03: Advancing research on the prevention, diagnosis, and management of post-infection long-term conditions RIA 40.00 6.00 to 8.00 5 16 Apr 2026
HORIZON-HLTH-2026-01-DISEASE-04: Development of novel vaccines for viral pathogens with epidemic potential RIA 45.00 Around 10.00 5 16 Apr 2026
HORIZON-HLTH-2026-01-DISEASE-09: Multisectoral approach to tackle chronic non-communicable diseases: implementation research maximising collaboration and coordination with sectors and in settings beyond the healthcare system (GACD) RIA 12.00 3.00 to 4.00 3 16 Apr 2026
HORIZON-HLTH-2026-01-DISEASE-11: Understanding of sex and/or gender-specific mechanisms of cardiovascular diseases: determinants, risk factors and pathways RIA 40.00 6.00 to 7.00 6 16 Apr 2026
HORIZON-HLTH-2026-01-DISEASE-15: Scaling up innovation in cardiovascular health CSA 2.00 Around 2.00 1 16 Apr 2026

 

Destination – Ensuring equal access to innovative, sustainable, and high-quality healthcare
HORIZON-HLTH-2026-01-CARE-01: Public procurement of innovative solutions for improving citizens’ access to healthcare through integrated and personalised approaches PPI 25.00 3.00 to 8.00 4 16 Apr 2026
HORIZON-HLTH-2026-01-CARE-03: Identifying and addressing low-value care in health and care systems RIA 45.00 Around 10.00 5 16 Apr 2026
HORIZON-HLTH-2026-04-CARE-04: Enhancing and enlarging the European Partnership on Personalised Medicine (EP PerMEd) (Top-up) COFUND 15.00 Around 15.00 1 16 Apr 2026

 

Developing and using new tools, technologies and digital solutions for a healthy society

HORIZON-HLTH-2026-01-TOOL-03: Integrating New Approach Methodologies (NAMs) to advance biomedical research and regulatory testing RIA 50.00 5.00 to 8.00 7 16 Apr 2026
HORIZON-HLTH-2026-01-TOOL-06: Support to European Research Area (ERA) action on accelerating New Approach Methodologies (NAMs) to advance biomedical research and testing of medicinal products and medical devices CSA 3.00 Around 3.00 1 16 Apr 2026

 

Destination – Maintaining an innovative, sustainable, and competitive EU health industry

HORIZON-HLTH-2026-01-IND-03: Regulatory science to support translational development of patient-centred health technologies RIA 20.00 4.00 to 6.00 4 16 Apr 2026